R & D Overview
Industry Connect
Ph.D. Scholar Details
MoU's
Research QIP and Infrastructure Development Grants
| Sr. No. | Name of Funding Agencies | Type of Project | Amount Sanctioned (Rs. in Lakhs) | Link to Funding Agencies |
|---|---|---|---|---|
| 1. | Department of Science & Technology, New Delhi | DST FIST-Infrastructure Development | 45.0 | https://dst.gov.in/ |
| 2. | All India Council for Technical Education, New Delhi | Research Projects | 30.37 | https://www.aicte-india.org/ |
| 3. | All India Council for Technical Education, New Delhi. | Infrastructure Development | 25.18 | https://www.aicte-india.org/ |
| 4 | All India Council for Technical Education, New Delhi. | Industry Institute Partnership Cell | 8.0 | https://www.aicte-india.org/ |
| 5 | All India Council for Technical Education, New Delhi. | FDP ,STTP | 4.63 | https://www.aicte-india.org/ |
| 6 | Rajiv Gandhi Science and Technology Commission, Mumbai. | Research Project | 16.7 | https://rgstc.maharashtra.gov.in/sanctioned-projects |
| 7 | Savitribai Phule Pune University, Pune. | Research Project | 56.9 | http://www.unipune.ac.in/ |
| 8. | Savitribai Phule Pune University, Pune. | Quality improvement Programmes | 21.20 | http://www.unipune.ac.in/ |
| 9. | Savitribai Phule Pune University, Pune | Infrastructure Development | 24.85 | http://www.unipune.ac.in/ |
| 10. | Industries and Institutes | Consultancey and Services | 121.32 | - |
Publications/Presentations/Research Collaborations
| Sr. No. | Publications/Presentations/Research Collaborations | Number |
|---|---|---|
| 1 | Publications | 367 |
| 2 | Presentations | 193 |
| 3 | RResearch Collaborations: Vipra Pharmaceuticals, Pune, Rajaswa Pharmaceuticals Pvt. Ltd., Pune, Passiflora Laboratories Pvt. Ltd, Pune, KITE-Ai Technologies Private Limited, Pune, SIEC Education Pvt. Ltd., Pune, Dr. D.Y Patil Dental College & Hospital, Pune, University of Witwatersrand, Faculty of Health sciences, Johannesburg, South Africa, MCIII - Marathwada Mitramandal Centre for Invention innovation Incubation, Pune in collaboration with Tata Technologies Ltd. and Science & Technology Park, Pune, Mprex Healthcare Pvt. Ltd. Pune, Srujan Healthcare Pvt. Ltd., Pune, Matruj Ayurveda Pharmacy Pvt. Ltd., Pune, NuLife Pharmaceuticals, Pune, SG Phyto Pharma Pvt. Limited, Kolhapur, Reve Pharma, Nashik, MB Healthcare, Pune, Chakan Life Sciences Pvt. Limited, Pune, Ari Healthcare Pvt. Limited, Pune, Callidus Research Laboratories Pvt. Ltd., Pune, PRADO (Preclinical Research and Development Organization Private Limited), Pune, BVG India Limited, Pune, Maharashtra, Pune District Education Association’s College of Ayurved and Research Centre, Pune, Maharashtra. | 21 |
Research Interest
SEMINAR/WORKSHOPS/CONFERENCES ORGANIZED
| Sr. No. | Academic Year | FDP/STTP/SEMINARS / WORKSHOPS/CONFERENCES ORGANIZED | Total | ||||
|---|---|---|---|---|---|---|---|
| District / Local | State | National | Workshops | Conferences | |||
| 1. | 2023–24 | - | - | - | 24 | – | 24 |
| 2. | 2022–23 | - | 1 | - | 27 | – | 28 |
| 3. | 2021–22 | 1 | - | 1 | 26 | – | 28 |
| 4. | 2020–21 | – | - | 2 | 12 | – | 14 |
| 5. | 2019–20 | – | 2 | – | 23 | – | 25 |
| 6. | 2018–19 | - | 1 | - | 17 | – | 18 |
| 7. | 2017–18 | – | – | 1 | 20 | 1 | 22 |
| 8. | 2016–17 | - | - | 1 | 16 | 1 | 18 |
| 9. | 2015–16 | - | - | 1 | 17 | - | 18 |
Ph.D. Scholars Award/Registration Details
| Sr.No. | Name of Research Scholar | Title of the Thesis | Year of Registration | Name of the Guide | Status |
|---|---|---|---|---|---|
| 1. | Mr. Prasad V.Kadam | Development and Evaluation of Topical Herbal Formulation for Anti-Inflammatory Activity | 2014-15 | Dr. Manohar J. Patil | Awarded (2019) |
| 2. | Mr. Mukesh P. Ratnaparakhi | Studies on solubility enhancement of poorly water soluble drugs by various pharmaceutical techniques | 2014-15 | Dr. Pravin. D. Chaudhari | Awarded (2019) |
| 3. | Mrs. Kavita N. Yadav | Development and Evaluation of Poly- herbal Topical Formulations | 2011-15 | Dr. Manohar J. Patil | Awarded (2019) |
| 4. | Ms. Pallavi V. Bhokare | Comparative Investigation of Phytochemical and Anti-diabetic Potential of Tabenae montana Species | 2019-20 | Dr. Manohar J. Patil | Pursuing |
| 5. | Ms. Madhavi A. Shivnikar | Delivery of CNS Acting Drug Through Nasal Route Using Nanostructured Carriers | 2019-20 | Dr. Avinash R. Tekade | Pursuing |
| 6. | Ms. Nirvi Gandhi | In vivo and In vitro Consideration to Support Herbal Product in Dry Powder Inhalers for Lung Diseases to Meet Current Needs | 2020-21 | Dr. Manohar J. Patil | Pursuing |
| 7. | Ms. Nirmala A. Musmade | Formulation Development and Evaluation of Drug Containing Cubosomes Loaded In situ Nasal Gel for Treating Alzheimer’s disease. | 2020-21 | Dr. Avinash R. Tekade | Pursuing |
| 8. | Ms. Vidya P. Thorat | Development and characterization of mucoadhesive nano- particulate drug delivery system for brain targeting through nasal route | 2020-21 | Dr. Avinash R. Tekade | Pursuing |
| 9. | Mr. Abhijeet K. Thorat | Design, Development And Characterization of Nanoparticulate Drug Delivery System for Efficient Targeting of CNS Through Nasal Route | 2021-22 | Dr. Avinash R. Tekade | Pursuing |
| 10. | Ms. Pratima Pokale | Development and Characterization of Anti Alzheimer's Drug loaded Nasal Mucoadhesive Nanoparticulate Drug Delivery System for Effective Management of | 2021-22 | Dr. Avinash R. Tekade | Pursuing |
| 11. | Ms. Pratima H. Pokale | Development and Characterization of Anti Alzheimer's Drug loaded Nasal Mucoadhesive Nanoparticulate Drug Delivery System for Effective Management of Alzheimer's Disease | 2021-22 | Dr. Avinash R. Tekade | Pursuing |
| 12. | Ms. Jyoti Lokhande | Enhancement of Solubility & Bioavailability of poorly water soluble drug using different Techniques | 2021-22 | Dr. Avinash R. Tekade | Pursuing |
| 13. | Ms. Shakila R. Shaikh | Pharmacological Screening of Herbal Plants for Wound Healing Activity in Experimental animals | 2021-22 | Dr. Pravin J. Patil | Pursuing |
| 14. | Ms. Arti Gite | Nanoformulation based nose to brain drug delivery for the treatment of neurodegenerative disease | 2021-23 | Dr. Rahul H. Khiste | Pursuing |
| 15. | Ms. Aishwarya Ambekar | Formulation, Method Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of antifungal drugs | 2022-23 | Dr. Rahul H. Khiste | Pursuing |
| 16. | Ms. Pramila Bhavar | Stability indicating analytical method development and validation of some anticonvulsant drugs in bulk and its dosage forms by chromatographic techniques | 2022-23 | Dr. Rahul H. Khiste | Pursuing |
| 17. | Ms. Shakila Shaikh | Pharmacological Screening of Herbal Plants for Wound Healing Activity in Experimental Animals | 2020-21 | Dr. Pravin J. Patil | Pursuing |
| 18. | Ms. Varsha Dhulsawant | Pharmacological Screening of Some Synthesized Novel Phenoxy Acetic Acid Analogues for Antihyperlipidemic Activity in Experimental Animals | 2020-21 | Dr. Pravin J. Patil | Pursuing |
| 19. | Mr. Vaibhav Mandale | QbD approach for Validation of Analytical Methods of Peptides and their Related Substances in Pharmaceutical Products | 2021-22 | Dr. Sampada D. Dalvi | Pursuing |
| 20. | Mr. Vikas Mugale | Isolation and Characterisation of Phytocontituents of Indigenous plants for potential biological activity | 2022-23 | Dr. Sampada D. Dalvi | Pursuing |
| 21. | Ms. Tai Yele | Magnetically modulated drug for targeting Anticancer therapy | 2022-23 | Dr. Sampada D. Dalvi | Pursuing |
| 22. | Ms. Priyanka Shelke | Design and Synthesis of Novel Derivatives of Pyrimidine based azetidinone molecules for their Anticancer Potential | 2022-23 | Dr. Babita A. Agarwal | Pursuing |
| 23. | Ms. Pranita Shankaratti | Design, Synthesis and Biological Evaluation of Novel Hybrid Analogues of some Antidiabetic Agents | 2022-23 | Dr. Babita A. Agarwal | Pursuing |
| 24. | Ms. Swati Kshirsagar | Design and Development of Novel Drug Delivery System for Inflammatory Conditions | 2022-23 | Dr. Mukesh P. Ratnaparkhi | Pursuing |
| 25. | Mr. Atul Suryavanshi | Biopharmaceutical approach in Solubility enhamcement of BCS Class II drugs | 2022-23 | Dr. Mukesh P. Ratnaparkhi | Pursuing |
| 26. | Mr. Shailendra Salvankar | Evaluation of Potential of Novel Lipid based nanocarrier system | 2022-23 | Dr. Mukesh P. Ratnaparkhi | Pursuing |
| 27. | Mr. Omkar Kolhe | Development and evaluation of nanostructured lipid carriers for the treatment of cancer | 2022-23 | Dr. Mukesh P. Ratnaparkhi | Pursuing |
MoUs with Research Organizations & Pharmaceutical Industries
| Sr.No. | Industry/Research Organisation with which MoU is signed | Year of signing & Renewal of MoU | Duration | Activities under MOU |
|---|---|---|---|---|
| 1. | BVG India Limited, Pune, Maharashtra | Sign. date- 02/01/2024 | 3 Years | Placement Internship, Industry Visit and Training, Collaborative Research |
| 2. | Pune District Education Association’s College of Ayurved and Research Centre, Pune, Maharashtra | Sign. date- 29/12/2023 | 3 Years | Collaborative Research, Consultancy and Services Industry Visit and Training | 3. | District Election Office Pune, Worship Earth Foundation, Pune, Maharashtra | Sign. date- 16/10/2023 | 3 Years | Voter Awareness and Promoting Ethical Electoral Participation |
| 4. | Tata Consultancy Services Ltd. Pune, Maharashtra | Sign. date- 12/10/2023 | 3 Years | Academic Interface Program (AIP),Training , Placement Student Training , Faculty Training |
| 5. | Bharati Vidyapeeth,Poona College of Pharmacy, Pune Maharashtra | Sign. date- 21/08/2023 | 3 Years | Training For Faculty &Students |
| 6. | Vipra pharmaceuticals, pune | sign. date-21/01/2023 | 3 Years | Consultancy and services industry visit and training |
| 7. | Rajaswa pharmaceuticals pvt. ltd. pune | Sign. Date- 21/01/2023 | 3 Years | Consultancy and services industry visit and training |
| 8. | Passiflora laboratories pvt. ltd, pune | Sign. Date- 21/01/2023 | 3 Years | Consultancy and services industry visit and training |
| 9. | Kite-ai technologies private limited, pune | Sign. Date- 11/01/2023 | 3 Years | Training & career guidance on clinical trails & data analytics |
| 10. | SIEC Education Pvt. Ltd Pune Maharashtra | Sign. Date-20/07/2022 | 3 Years | Career Guidance, Consultancy Services for Higher Education at Abroad |
| 11. | Dr. D.Y Patil Dental College Hospital Pune Maharashtra | Sign. Date-30/06/ 2022 | 3 Years | Collaborative research Projects Regenerative Medicine Lab. |
| 12. | University of Witwatersrand, Faculty of Health sciences, Johannesburg, South Africa | Sign. Date-15/06/2022 | 3 Years | Advanced Drug Delivery Platform |
| 13. | MCIII - Marathwada Mitramandal Centre for Invention innovation Incubation, Pune in collaboration with Tata Technologies Ltd. and Science Technology Park | Sign. Date-06/09/2021 | 1 Years | Invention innovation Incubation For technology startups and entrepreneurs |
| 14. | Mprex Healthcare Pvt. Ltd. Pune, Maharashtra | Sign. Date-01/01/2021 | 3 Years | Consultancy & Services Industry Visit Collaborative research Projects |
| 15. | Srujan Healthcare Pvt. Ltd. Pune, Maharashtra | Sign. Date-01/12/2020 | 3 Years | Collaborative research Projects Consultancy & Services Industry Training Industry Visit Placement |
| 16. | Matruj Ayurveda Pharmacy Pvt. Ltd. Pune, Maharashtra | Sign. Date-01/03/2020 | 3 Years | Placement Industry Training Industry Visit Consultancy & Services Collaborative research Projects |
| 17. | Rubicon Skill Development Pvt.Ltd. Pune, Maharashtra | Sign. Date- | 2 Years | Employability Skill Development Programs |
| 18. | NuLife Pharmaceuticals, Pune, Maharashtra | Renew Date01/11/2019, 01/11/2016 Sign. Date18/10/2013 | 3 Years | M. Pharm Dissertation Project Placement Industry Training Industry Visit Consultancy & Services Industry Training Industry Visit |
| 19. | SG Phyto Pharma Pvt. Limited, Kolhapur. Maharashtra | Renew Date 01/11/2019, 01/11/2016 Sign. Date18/10/2013 | 3 Years | Consultancy & Services Industry Visit Industry Training Collaborative research Projects |
| 20. | Reve Pharma, Nashik, Maharashtra | Renew Date - 01/11/2019, 01/11/2016 Sign. Date - 18/10/2013 | 3 Years | M. Pharm Dissertation Project Consultancy & Services Industry Visit Industry Training |
| 21. | MB Healthcare, Pune, Maharashtra | Renew Date01/11/2019 Sign. Date01/11/2016 | 3 Years | Consultancy & Services Collaborative research Projects |
| 22. | Chakan Life Sciences Pvt. Limited, Pune, Maharashtra | Renew Date 01/11/2019 Sign. Date01/11/2016 | 3 Years | Placement Consultancy & Services Industry Visit Industry Training Collaborative research Projects |
| 23. | Ari Healthcare Pvt. Limited, Pune, Maharashtra | Renew Date- 01/07/2022, 01/07/2021, 01/07/2020, 08/07/2019 Sign. Date- 01/08/2013 | 2 Years | M. Pharm Dissertation Project Placement Consultancy & Services Industry Visit Collaborative research Projects |
| 24. | Callidus Research Laboratories Pvt. Ltd. Pune | Renew Date- 21/01/2022 Sign. Date 20/01/2019 | 3 Years | M. Pharm Dissertation Research Project Placement Consultancy & Services Industry Visit Collaborative research Projects |
| 25. | Prado Pvt. Limited, Pune, Maharashtra | Renew Date- 01/11/2021, Sign. Date 01/11/2016 | 5 Years | Consultancy & Services Collaborative research Projects |
Department of Pharmaceutics & Pharmaceutical Quality Assurance
The area of research interest of the faculty includes CNS targeting, nasal mucoadhesive drug delivery, transdermal drug delivery system, pulsatile drug delivery, floating drug delivery system, colon targeted drug delivery, microencapsulation, solubility enhancement, crystal engineering, taste masking & mouth dissolving systems, preservation of biomolecules, micro & nano-particulate drug delivery system, sustained/ controlled drug delivery system and self-emulsified drug delivery system.
Recent/Highlighted Publications
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1. Solid–Liquid Equilibrium Study of Itraconazole in Diethylene Glycol: Water
Mixtures at 298.15 K Using Extended Hildebrand Solubility
ApproachSachin K. Jagdale· Rajesh B. Nawale, Chemistry Africa, 2024; 7; 151-
164. 766.
2. Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer’s disease Avinash R. Tekade, Mayuri R. Suryavanshi, Ashutosh B. Shewale &Vilas S. Patil , Drug Development and Industrial Pharmacy, 2023: 49(9):590-600.
3. Nanostructured cubosomal in situ nasal gel for the treatment of migraineAvinash Tekade, Pratiksha Ghodke, Ashvini Patange, Pravin Patil, Journal of Drug Delivery Science and Technology,2023:87:104797.
4. Formulation, Optimization and Evaluation of Transdermal Patch by Loading Electro Spun nanofiber of Griseofulvin Dipti D. Kadam, Mukesh P. Ratnaparkhi, Prasad V. Kadam, Swapnil R. Shinde, Omkar V. Kamble, European Chemical Bulletin 2023; 12(9):813-828.
5. Self-microemulsifying Drug Delivery System: Special Emphasis on vvarious oils used in SMEDDS ,Mukesh ratnaparkhi, Rajnandini Ahire, Hrushikesh Shinde, Shailendra Salvankar, International Journal of Pharmaceutical Sciences and Research,2023;14(2): 579-589.
6. Nanostructured Lipid carriers: The Advanced Lipid Carriers and Their Applications Shailendra Salvankar, Akshada A. Aghav, Devang S. Mahale, Shital S. Kshirsagar, International Journal of Pharmaceutical Sciences and Research, 2023; 14(2): 547-561..
7. Formulation and Evaluation of Moxifloxacin Dry Powder Inhaler Combined with Mucolytic Agent for Pulmonary Diseases, Ratnaparkhi M. P.* Kamble O. V., Salvankar S. S., Shinde S. R., Kulkarni G. M., Shewale A. B.,Kadam D. D., Shaikh A. J., International Journal of Drug Delivery Technology 2023; 13(3):818-824.
8. Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin Calcium by Solid Dispersion Technique Using a Modified Natural Polymer as a Hydrophilic Carrier, Avinash R. Tekade, Sneha U. Mathapati, Mukesh P. Ratnaparkhi, Gajanan M. Kulkarni, Journal of Pharmaceutical Innovation 2023;18;2185-2195.
9. Tekade AR, Mittha PS, Pisal CS. Nanostructured lipid carriers for nose to brain delivery targeting CNS: Diversified role of liquid lipids for synergistic action. Advanced Pharmaceutical Bulletin, doi: 10.34172/apb.2022.078.
10. A. R. Tekade and G. D. Avhad, A review on cubosomes: A novel approach for drug delivery, International Journal of Pharmaceutical Sciences and Research, 2022; 13(2): 579- 588.
11. Avinash R. Tekade , and Prasad Y. Kolapkar, A mini review on advances in transdermal drug delivery system, International Journal of Pharmaceutical Sciences and Research, 2022; 13(1): 70-85.
12. Sachin K. Jagdale, Rajesh B. Nawale Experimental measurement – correlation of solubility and dissolution thermodynamics study of itraconazole in pure monosolvents at various temperatures, Drug Development and Industrial Pharmacy, 2021, 1-4.
13. Ratnaparkhi M.P., Andhale R.S., Karnawat G.R., Nanofibers – A Newer Technology, Research Journal of Pharmacy and Technology 2021; 14 (4), 2321- 2327.
14. Ratnaparkhi M.P., Karnawat G.R., Andhale R.S., Natural Polymers in Fast Dissolving Tablets, Research Journal of Pharmacy and Technology 2021; 1-6.
15. Sachin Jagdale, Simran Karekar, Bird’s eye view on aquasomes: Formulation and application of aquasomes Journal of Drug Delivery Science and Technology, 2020, 58:1-14.
16. Avinash Tekade, Jyoti Yadav. A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs, Advanced Pharmaceutical Bulletin, 2020, 10(3), 359-369 359-369.
17. Sachin Jagdale, Rajesh Nawale, Extended Hildebrand solubility Approach: prediction and correlation of the solubility of Itraconazole in Triacin: water mixtures at 298.15 K Turkish Journal of Pharmaceutical Sciences, 2020 Apr; 17(2): 228–234.
18. Sandip D. Firke, Komal R. Bhoi, Kiran R. Patil, Shubham D. Jayswal, Avinash R. Tekade, &; Shailesh S. Chalikwar, A State-of-the-art Review on Applications of Different Analytical Techniques for Some ACE Inhibitors, Analytical ChemistryLetters, 2020, 10 (1) : 60 – 79.
Department of Pharmaceutical Chemistry & Pharmaceutical Quality Assurance
The area of research interest of faculty includes Biomaterials, Polymeric scaffolds for regenerative medicine, Microfluidic systems, Medical devices, Analytical Method development, Analytical process validation, Stability Indicating Method for Bulk Drugs and their various Formulations, Bioanalytical Method Development, SAR Based Drug Design, Heterocyclic Chemistry, Development of Novel Analogues for anti-inflammatory, anticancer, CNS agents, Multicomponent Reactions, Green Chemistry.
Highlighted publications
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1. Avirup Chakarborty, Ravindra V. Badhe, Muhammad Abbas, Anjali Chauhan, Abhishek
Jaiswal, Rameesha Fareed, VInay Kumar, Yangtao Duan, Nalok Datta. Role of
Exosomal RNA in wound healing and tissue repair (Chapter 13) in Exosomal RNA Role
in Human Diseases and Therapy, Eds D. Bhattacharya, M. Mukhopadhyay, K. Turksen.
Elsevier Academic Press, Cambridge, Massachusetts, USA, 2024, pp 295-323.
(Paperback ISBN: 9780443140082; eBook ISBN: 9780443140075).
2. Sachin Jagdale, Babita Agarwal, Abhishek Dixit, Saurabh Gaware. Chitosan as excellent bio-macromolecule with myriad of anti-activities in biomedical applications – A review. International Journal of Biological Macromolecules. 2024, 257(2), 128697. [https://doi.org/10.1016/j.ijbiomac.2023.128697]. (Elsevier/IF – 8.2)
3. Hemalatha Kanniyappan, Kai-yuan Cheng, Ravindra V. Badhe, Mozart Neto, Divya Bijukumar, Mark Barba, Robin Pourzal, Mathew Mathew, Investigation of cell- accelerated corrosion (CAC) on the CoCrMo alloy with segregation banding: Hip implant applications, Journal of the Mechanical Behavior of Biomedical Materials, 2024, 106449. [https://doi.org/10.1016/j.jmbbm.2024.106449]. (Elsevier/IF – 4.626)
4. Babita Agarwal, Sachin Jagdale, Prasad Kadam, Santaji Nalawade, Shivaji Mhaske, Pooja Dale. Development and Validation of Stability Indicating RP-HPLC Method for estimation of Glycpyrrolate and Neostigmine in Bulk and Injection. Journal of Chromatographic Science. 2024, 62(3):213-221. [https://doi.org/10.1093/chromsci/bmad035]. (IF – 1.3)
5.Ravindra V. Badhe, Abhinav Chatterjee, Divya Bijukumar, Mathew T. Mathew. Current advancements in bio-ink technology for cartilage and bone tissue engineering. BONE, 2023, 171, 116746. (Elsevier/IF – 4.626). [https://doi.org/10.1016/j.bone.2023.116746]. 6. Archana A. Gupta, Supriya Kheur, Ravindra V. Badhe, Saranya Varadarajan, Madhura
Shekatkar, Vikrant R. Patil, Anagha Godse, Ramesh Bhonde. Potential use of anti- cancer drugs coated scaffolds for local drug delivery in cancer cell lines. Oral Oncology Reports. 2023, 6, 100032. (Elsevier). [https://doi.org/10.1016/j.oor.2023.100032].
7. Nilesh S. Kulkarni, Vidyaranee B. Ingle, Shashikant N. Dhole, Rahul H. Khiste, Rahul S. Shivarkar, Manoj K. Munde. Development of Fast-dissolving Oral Dosage Form as Tablet using Binder as Vigna Mungo Mucilage and Oral Film using Solvent Casting Technique: Comparative Study. Asian Journal of Pharmaceutics, 2023, 17 (4), 754-762. [https://doi.org/10.22377/ajp.v17i04.5097]
8. Saylee Ganorkar, Aditya Bhavsar, Pramod Sakpal and Rahul Khiste. Chromatographic Development and Validation of High-performance Thin Layer Chromatography Method for Concurrent Estimation of Azelnidipine and S (-) Metoprolol Succinate in Bulk and Tablets. 2023, 2023(6), e150923221186. [https://doi.org/10.2174/2666001603666230915161005]
9. Rahul H. Khiste, Nilesh Kulkarni, Shruti Burad, Manojkumar Munde. A concise literature review on Niosome Drug Delivery from Ancient to Recent. Asian Journal of Pharmaceutics, 2023,17(1), 20. [https://doi.org/10.22377/ajp.v17i1.4710].
10. Pramod H. Sakpal, G. S. Mhaske, Ashim Sen, Ashish Shah, Dhanya Sen, Ganesh R. Phadtare, Shyam S. Awate, R. H. Khiste, Vishnu S. Neharkar. Synthesis, Cytotoxicity, PDGFR Inhibitory activity and docking study of novel 2-aminoquinoline-3-carboxamide derivatives as potential anticancer agents. European Chemical Bulletin. 2023, 12 (1), 292-305. [https://doi.org/10.31838/ecb/2023.12s7.033]
11. Sayali Ganorkar, Nilesh Kulkarni, Rahul Khiste. A review on recent approaches for the use of different analytical techniques to analyze some calcium channel blocker and their combinations with other antihypertensive drugs. Current Indian Science. 2023, 2023 (1), e2210299X250401. [https://doi.org/10.2174/012210299X250401231010114247].
12. Pradnya Pawar, Shilpi Kondaskar. Formulation and Evaluation of Vanishing Cream using Natural Extracts. International Journal of Science and Research (IJSR). 2022 11(8), 13-16. [https://doi.org/10.21275/MR22727183518]
13. Rahul H. Khiste, G. S. Mhaske. In-Silico Identification of Novel Quinoline-3- carboxamide Derivatives Targeting Platelet Derived Growth Factor Receptor. Current Cancer Therapy Reviews. 2022, 18 (2), 131 – 142. [https://doi.org/10.2174/1573394718666220421111546]
14. Rahul H. Khiste, Ganesh S. Mhaske, Ashim K. Sen, Ashish Shah, Dhanya B. Sen, Sagar A. Jadhav. Synthesis, Characterization and in vitro Anticancer Evaluation of Novel Quinoline-3- Carboxamide Derivatives as Inhibitors of PDGFR. NeuroQuantology. 2022, 20(8), 7967- 7980. [https://doi.org/10.14704/nq.2022.20.8.NQ44823].
15.Babita Agarwal, Sachin Jagdale, Santosh Gandhi, Forced Degradation Study of Sofosbuvir: Identification of Degradation Products by LC-ESI-MS, Indian Journal of Pharmaceutical Education and Research. 2022, 56 (2s), s181-s188. (IF - 0.638). [https://doi.org/10.5530/ijper.56.2s.89].
16. Nilesh S. Kulkarni, Mukta A. Kulkarni, Rahul H. Khiste, Mohini C. Upadhye, and Shashikant N. Dhole. Development and Evaluation of Floating Microspheres of Sumatriptan Succinate using Ethyl Cellulose and Mucilage Extracted from Vigna Mungo’ published in Journal of Pharmaceutical Research International. 2021, 33(43A), 24-36, [https://doi.org/10.9734/jpri/2021/v33i43A32461].
17. Rahul H. Khiste, G. S. Mhaske, S. S. Shinde, S. A. Jadhav. Indole 1,2,3,4- tetrahydropyrimidinone: Synthesis, Characterization and It’s Biological Applications. International Journal of Pharmaceutical Sciences and Research. 2021, 12 (1), 963-972. [https://doi.org/10.13040/IJPSR.0975-8232.12(2).963-72].
18. Rahul H. Khiste, Nilesh S. Kulkarni, Manojkumar K. Munde. A comprehensive Review on Application of Microwave Irradiation for preparation of Inclusion complexes with Cyclodextrins. Research Journal of Pharmacy and Technology. 2021, 14(2), 1131-1136. [https://doi.org/10.5958/0974-360X.2021.00203.1].
19. Rahul H. Khiste, Nilesh S. Kulkarni, Manojkumar K. Munde Nilkanth Bhapkar. A Review on Applications of Hydroxy Propyl Methyl Cellulose and Natural polymers for the development of modified release drug delivery systems. Research Journal of Pharmacy and Technology. 2021, 14(2), 1163-1170. [https://doi.org/10.5958/0974- 360X.2021.00208.0].
20. Pramod H. Sakpal, A. R. Chabukswar. Accelerated Degradation Method Development and Validation for Determination of Amlodipine and Atorvastatin in Combination Dosage Form of Tablet. International Journal of Pharmaceutical Education and Research. 2021, 55(02), 598-606. [https://doi.org/10.5530/ijper.55.2.99]
21. Sampada D. Dalvi, Sohan S Chitlange, Pramod L. Ingale. Derivitisation of Pregabalin for simultaneous estimation with methylcobalamine using Ultra Violet Spectroscopy. Indian Drugs. 2021, 58 (11), 70-72. [https://doi.org/10.53879/id.58.11.11899]. 22. Rahul H. Khiste,Nilesh S. Kulkarni, Manojkumar K. Munde. Development and
validation of Novel Analytical method for Empagliflozin and Metformin Hydrochloride in Bulk and Pharmaceutical dosage form by Four Different Approaches Simultaneous equation approaches using UV spectroscopy. 2020, 13(3), 1236-1242. [https://doi.org/10.5958/0974- 360X. 2020. 00228.0]
23. Babita A. Agarwal and S. V. Gandhi. Development of Validated Stability-indicating RP- HPLC Method for Determination of Novel Directly Acting Antiviral agent and Characterization of its Degradants by LC–ESI–MS, Indian Journal of Pharmaceutical Education and Research, 2020, 54(4),1159-1168. (Impact Factor 0.638). [https://doi.org/10.5530/ijper.54.4.212].
24. Sampada D. Dalvi, Pramod L. Ingale, Dalvi Sanjay M. Development and method validation of stability indicating assay method of dutasteride by using UV-Vis spectroscopy. Indian Drugs. 2020, 57 (12), 36-40. [https://doi.org/10.53879/id.57.12.11575].
25.Pramod H. Sakpal, A. R. Chabukswar. Stability indicating RP - HPLC method development and validation for simultaneous estimation of Amlodipine and Chlorthalidone in bulk and tablet dosage form. International Journal of Pharmaceutical Sciences and Research. 2020, 11(5), 2161-2168. [https://doi.org/10.13040/IJPSR.0975- 8232.11(5).2161-68]
Department of Pharmacognosy
The area of research interest includes Phytochemistry, Pharmacological screening of Herbal Drugs (Asthma, Diabetes, MSD) and Standardization of Herbal Drugs, formulation and Development of Herbal/Ayurvedic formulations, Analytical method development of Herbal/Ayurvedic formulations (Spectroscopic & Chromatographic). Ecological Development, Biodiversity and conservation,Callus Culture & Genetic Transformation.
Highlighted Publications
- 1. Prasad Vijay Kadam, Damini Kallyanrao Giram, Sameer Khamroddin Shaikh,
Kavita Nilesh Yadav, Abhijit Sampatrao Karanje, Manohar Janardhan Patil,
Pharmacognostic, Chemical Characterization Studies on Oyster Mushroom
(Pleurotus ostreatus). Pharmacognosy Research2023; 15(3):1-6
2. Prasad Vijay Kadam, Prachi Vikas Bhapkar, Sameer Khamroddin Shaikh, Kavita Nilesh Yadav, Damini Kallyanrao Giram, Abhijit Sampatrao Karanje, Bryonia laciniosa: A Ethnopharmacological Approach of Ayurvedic Shivlingi, Pharmacognosy Research. 2023; 11(3):1-10
3. Babita Agarwal, Sachin Jagdale, Prasad Kadam, Pramod Sakpal, Santaji nalawade, Shivraj Mhaske, Pooja Dale, Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Glycopyrrolate and Neostigminein Bulk and Injection, Journal of Chromatographic Science (Online Ahead of Print) (Impact factor 1.897)
4. Prasad Kadam, Kavita Yadav, Abhijit Karanje, Damini Giram, Rutuja Mukadam Manohar Patil, The Food and Medicinal Benefits of Oyster Mushroom (Pleurotus Ostreatus) : A Review, International Journal of Pharmaceutical Sciences and Research. 2023; 14(02), 883-890
5. Prasad Kadam, Kavita Yadav, Abhijit Karanje, Damini Giram, Rutuja Mukadam Manohar Patil, Karkatshringi (Pistacia Integerrima): Phytopharmacological Review, International Journal of Pharmaceutical Sciences and Research. 2023; 14(02), 1063-1070
6. Pallavi Karanje, Vishwajeet Ghorpade, Ajay Namdeo, Rajendra Doijad, Abhijit Karanje Comparison of techniques for the extraction of Camptothecin from Tabernaemontana species Natural Product Research, Formerly Natural Product Letters, Volume 37, 2021 - Issue 2 Page No. 322-327. (Impact Factor-2.510)
7. Snehal Kashid, Ashish Suttee, Prasad Kadam, Gopal Lal Khatik, Ramesh Kasarla, An in- silico studies for immunomodulatory potential of phytoconstituents from a naturally occurring herb nigella sativa. Pharmacophore, 2022, 13(5) 14-26 (Impact Factor 2.16)
8. Sanjay U Nipanikar, Manohar J Patil, Prasad V Kadam, In-vivo evaluation of chondroprotective activity of Ariflex tablet in comparison with aceclofenac tablet and chondroitin sulfate/glucosamine (CG) in monosodium iodoacetate-induced osteoarthritis in rats, Journal of Indian System of Medicine. 2022, 10 (03) 164- 175.
9. Prasad Kadam, Manohar Patil, Kavita Yadav. A Review on Phytopharmacopial Potential of Epilobium angustifolium, Pharmacognosy Journal, 10 (06), 2018, 1076-1078
10. Prasad V Kadam, Kavita N Yadav, C L Bhingare, Manohar J Patil. Standardization and quantification of curcumin from Curcuma longa extract using UV visible spectroscopy and HPLC, Journal of Pharmacognosy and Phytochemistry. 2018; 07(05), 1913-1918.
11. P. V. Kadam, K. N. Yadav, C. L. Bhingare M. J. Patil. Development and Validation of a HPLC Analytical Method for Determination of Ellagic acid in Epilobium angustifolium Extract, International Journal of Pharmaceutical Sciences and Research, 2019; 10(03), 1300-1306
12. K. N. Yadav, P. V. Kadam, C. L. Bhingare M. J. Patil. Quality Assessment of Vranropan Taila: an Ayurvedic Siddha Taila for Wound Healing and Anti-Mark Property, International Journal of Pharmaceutical Sciences and Research, 2019; 10(03), 1263-1268.
13. Kavita N Yadav, Prasad V Kadam, Chandrashekhar L Bhingare, Manohar J Patil. Quality assessment of Syzygium aromaticum A pharmacognostic and phytochemical approach, Journal of Pharmacognosy and Phytochemistry. 2018; 07(05), 720-724.
14. K. N. Yadav, P. V. Kadam, S. K. Jagdale M. J. Patil. Herbal Remedy for Wound Management: A Review, International Journal of Pharmacognosy, 2018; 05 (08), 100-110.
15. Mohini A Phanse, Manohar J Patil, Konde Abbulu, Synthesis, characterization and evaluation of the suppression of insulin resistance in Type-II diabetes mellitus animals by treatment with metal complex. Saudi Journal of Biological Sciences (2016), 23(03) 420-425.
16. Mohini A Phanse, Manohar J Patil, Konde Abbulu, Effect of Thespesia populnea on dexamethasone induced insulin resistance in mice, African Journal of Pharmacy and Pharmacology, (2014), 8(16) 429-432.
17. Kavita N Yadav, Prasad V Kadam, Jigna A Patel, Manohar J Patil, Strychnos potatorum: Phytochemical and pharmacological review, Pharmacognosy Reviews, (2014)1(08) (15)61.
18. Manohar J Patil, Prasad V Kadam, Phrmacognostic Study of Cucurbita moschata (Cucurbitaceae) Pharmacognosy Journal, (2013), 1-3.
19. G. Bhope, V.V. Kuber, D.H. Nagore, P.S. Gaikwad, and M.J. Patil, Development and Validation of RP-HPLC Method for Simultaneous Analysis of Andrographolide, Phyllanthin, and Hypophyllanthin from Herbal Hepatoprotective Formulation, Acta Chromatographica 25 (2013) 1, 159-169.
20. Prasad Vijay Kadam, Chandrashekhar Laxman Bhingare, Rohini yuvraj Nikam, Suchita Anil Pawar, Development and validation of UV spectrophotometeric method for the estimation of curcumin in cream formulation, Pharmaceutical Methods, (2013) 4 (02) 43-45.
21. BP Pimple, PV Kadam, MJ Patil, Ulcer healing properties of different extracts of Origanum majorana in streptozotocin-nicotinamide induced diabetic rats, Asian Pacific Journal of Tropical Disease, (2012) 2(4): 312-318.
22. P. Pimple, P. V. Kadam, M. J. Patil, Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats : Role of gastric mucosal glycoproteins and antioxidants, Asian Pacific Journal of Tropical Medicine, (2012) 412-420.
23. P. Pimple, A.N. Patel, P.V.Kadam, M.J.Patil, Microscopic evaluation and physicochemical analysis of Origanum majorana Linn leaves, Asian Pacific Journal of Tropical Disease, (2012) S897 – S903
24. G. Bhope, P.S. Gaikwad, V.V. Kuber, M.J.Patil, RP-HPLC Method for simultaneous constitution of boeravinone E and boeravinon B in Boerhaavia diffusa extract and its formulation, Natural Product Research, (2012), 1(4), I First.
25. P. Pimple, P. V. Kadam, M. J. Patil, Comparative antihyperglycaemic & antihyperlipidemic effect of Origanum majorana extracts in NIDDM rats, Oriental Pharmacy and Experimental Medicine, (2012) 12 (1) 41-50.
26. Ajay G. Namdeo, Ajay Sharma, Kavita N. Yadav, Rupali Gawande, Kakasaheb R. Mahadik, Maria Pilar Lopez- gresa, Hye Kyong kim, Young Hae Choi, Robert Verpoorte, Metabolic Characterization of Withania Somnifera from different region of India using NMR Spectroscopy, Planta medica, (2011),47-66.
27. Shrinivas G. Bhope, Vivek K. Ghosh,Vinod V. Kuber, Manohar J. Patil, Rapid Microwave- Assisted extraction and HPTLC-Photodensitometric Method for Quality Assessment for Boerhaavia diffusa L, Journal of AOAC International, (2011) 94 (03), 795-802.
28. Shrinivas G Bhope, Vinod V Kuber,Vivek K Ghosh, Manohar J Patil, A Novel Approach for the Quality Assessment and Stability Testing of Ayurvedic Polyherbal Formulations by HPTLC Fingerprint Method, Journal of Liquid Chromatography & Related Technologies, (2011) 34 (08)579-590.
29. S. Bhujbal, R. K. Nanda, R. S. Deoda, Dinesh Kumar, S. M. Kewatkar, L. S. More, M. J. Patil, Structure elucidation of a flavonoid glycoside from the roots of Clerodendrum serratum (L.) Moon, Lamiaceae, Brazilian Journal of Pharmacognosy (2010) 20(6): 1001-1002.
30. BK. Ghosh, D. H. Nagore, M.J.Patil, A. Prakash, Development and validation of a Method for Densitometric Analysis of Berberine in Herbal Extract and Polyherbal Formulation, Medical Principles and Practice, (2010) 19, 473- 478.
31. S. Gaikwad, S.G.Bhope, V.V. Kuber, M.J.Patil, Validated TLC Method for simultaneous quantitation of kutkoside and picroside I from kutki extract, Phytochemical Analysis, (2010)
Department of Pharmacology
Department of pharmacology is equipped with CPCSEA approved animal facility. There are different instruments and equipment’s available to enable research in different areas of pharmacology. Focus of research at department of pharmacology includes:
Screening of drugs for wound healing activity. Screening of drugs for anti-allergic and anti-asthmatic activity. Screening of drugs for anti-diabetic activity. Screening of drugs for anti-inflammatory and anti-arthritic activity. Screening of drugs for central nervous system related disorders. Screening of drugs for cardiovascular disorders. Safety pharmacology. Toxicology Pharmacy practice. Formulation development related pharmacological studies.Highlighted publications
- 1 Patil, P.J., Patil, V.S., Malu, J.S. and Aswale, D.M., 2024. Community Pharmacist’s Awareness, Knowledge and Attitude Towards use of Vitamin Supplements in Pimpri- Chinchwad Municipal Corporation (PCMC) Area of Pune, India: A Descriptive Cross Sectional Study. Indian Journal of Community Medicine, 49(1), pp.223-227. DOI: 10.4103/ijcm.ijcm_1014_22.
- 2 Bhong P. N., Patil P. J., and. Ghadage. P. K, 2023. Pathophysiology Of Asthma: A Review. International Journal of Pharmaceutical Sciences and Research, 14(9), pp. 4373-4383. DOI link: http://doi.org/10.13040/IJPSR.0975-8232.14(9).4373-83
- 3 Bhong, P.N., Nilofar, N.S., Pratibha, M.R. and Madhavi, B.S., 2021. In-vitro and in-vivo Evaluation of Anti-asthmatic Activity of Eugenia jambolana bark. Research Journal of Pharmacy and Technology, 14(6), pp.3337-3342. DOI : 10.52711/0974- 360X.2021.00580
- 4 Shivnikar M. A., and P. N. Bhong., 2020. Formulation and Evaluation of Controlled Porosity Osmotic Tablet of Verapamil Hydrochloride, International Journal of Phrmaceutical Sciences and Research, 11(6), pp. 1000-08. DOI link: http://dx.doi.org/10.13040/IJPSR.0975-8232.11(6).2976-83
- 5 Patil, P.J., Patil, V.S., Chaudhari, R.D. and MALU, J., 2020. Awareness, Knowledge and Attitude about Dengue Among Society. Int. J. Curr. Pharm. Res, 12(6), pp.36-40. DOI: https://doi.org/10.22159/ijcpr.2020v12i6.40278
- 6 Patil, P.J., Patil, V. and Chavan, R., 2020. Awareness, knowledge and attitude about antibiotics use among society. Res J Pharm Technol, 13(11), pp.5202-06.
- 7 Patil, P.J., 2020. Antimicrobial Drug Resistance: A Review. World Journal of Pharmaceutical Sciences, 8(9), pp.169-174..
- 8 Patil, P. J.,Patil, V.S. and Bhore, P., 2020. Prescription analysis of hypertensive patients and awareness among physician regarding antihypertensive drug. Int J Curr Pharm Res, 12(2), pp.124-128. DOI: http://dx.doi.org/10.22159/ijcpr.2020v12i2.27521.
- 9 Patil, P.J, and Mohanta G.P.., Neuroprotective effect of petroleum ether, methanolic and aqueous extracts of flower heads of Sphaeranthusindicus on lipofuscinogenesisand fluorescence product in brain of D-galactose induced aging accelerated mice, Oriental Pharmacy and Experimental Medicine, 13:301–306, (2013)
- 10 Patil, P.J, Nagore, D., Ambikar, D., Patil, M., Nipanikar, S. and Kanjilal, S., 2016. Evaluation of wound healing potential of various wound healing creams in fresh, diabetic and burn wound models. Eur J Pharm Med Res, 3(1), pp.248-58.
- 11 Ambikar, D.B. and Mohanta, G.P., 2014. Evaluation of neuropharmacological activity of petroleu 10 m ether, methanolic and aqueous extracts of flower heads of Sphaeranthus indicus in mice. Journal of Applied Pharmaceutical Science, 4(4), pp.112-118. DOI 10.7324/JAPS.2014.40419
- 12 Patil, P.J., Patil, M.J., Patil, V.R., Deshmukh, T.A. and Band, S.S., 2013. A survey on awareness of Fixed Dose Combinations (FDCs) among patients, physicians and pharmacists at Pune and Beed (India). Indian Journal of Pharmacy Practice, 6(3). Pp 49- 52.
- 13 Ambikar, D.B. and Mohanta, G.P., 2013. Effect Of Dried Fruit Extract of Benincasa Hispida On Brain Behaviour In Laboratory Animals. Journal of Cell & Tissue Research, 13(1), pp 3519-3524.
- 14 Ambikar, D.B.and Mohanta, G.P., 2013. Neuroprotective effect of petroleum ether, methanolic and aqueous extracts of flower heads of Sphaeranthus indicus on lipofuscinogenesis and fluorescence product in brain of D-galactose induced aging accelerated mice. Oriental Pharmacy and Experimental Medicine, 13, pp.301-306.
- 15 Ambikar, D.B., Harle, U.N., Khandare, R.A., Bore, V.V. and Vyawahare, N.S., 2010. Neuroprotective effect of hydroalcoholic extract of dried fruits of Trapa bispinosa Roxb on lipofuscinogenesis and fluorescence product in brain of D-galactose induced ageing accelerated mice. Indian Journal of Experimental Biology, 48(4). 378-82.
- 16 Patil, P.J., Ambikar, D.B., Bojgar, S.M. and Patil, M.J., 2012. Status of Hospital Pharmacy in the Pimpri-Chinchwad Region of Pune (India)–A Survey. Indian journal of Hospital Pharmacy, pp. 49 (1), pp. 103-105.
- 17 Patil, P.J., Chaudhari, S.P. and Ghodekar, S.V., 2012. Article Details Evaluation of Wound Healing activity of Silver Sulfadiazine Emulgel (1%) in the Rat burn wound Model and its skin irritation study. Indian Drugs, 49(11), pp. 40-43.
Overview of Research at MMCOP
| 1 | Rajiv Gandhi Science and Technology Commission, Government of Maharashtra Sponsored Research Project Grant | Rs. 16.7 Lakh |
| 2 | DST FIST(Infrastructure and Development Fund) | Rs.45 Lakhs |
| 3 | Sponsored Research Projects | 32 (Rs.77.12 Lakhs) |
| 4 | Sponsored AICTE QIP Schemes & | 02 (Rs.22.00 Lakhs) |
| MODROBS | Rs.24.20 Lakhs | |
| IIPC | Rs.8.00 Lakhs | |
| 5 | Sponsored other QIP Schemes | Rs. 30.79 Lakhs |
| 6 | No. of Publications | 278 |
| 7 | No. of Presentations | 185 |
| 8 | Research Collaborations | SG Phytopharma Pvt. Ltd. Kolhapur. Reve Pharma, Sinnar, Nashik. Ari Healthcare Pvt. Ltd., Pune. Nulife Pharma., Pimpri, Pune. Scitech Laboratories Pvt. Ltd, Sinnar, Nashik. Chakan Life Sciences Pvt. Ltd., Pune. MB Healthcare, Pune. Preclinical Research and Development Organization (PRADO), Pune. |
Research Interest
SEMINAR/WORKSHOPS/CONFERENCES ORGANIZED
| Sr. No. | Academic Year | Seminars / Workshops/Conference Organized | Total | ||||
|---|---|---|---|---|---|---|---|
| District / Local | State | National | Workshop | Conferences | |||
| 1 | 2019-20 | – | 1 | 1 | 4 | – | 6 |
| 2 | 2018-19 | – | 1 | – | – | – | 1 |
| 3 | 2017-18 | 1 | – | 1 | – | – | 2 |
| 4 | 2016-17 | – | – | 1 | – | 1 | 2 |
| 5 | 2015-16 | – | – | 1 | – | – | 1 |
| 6 | 2014-15 | – | – | 1 | – | – | 1 |
| 7 | 2013-14 | – | 1 | 1 | – | 1 | 3 |
| 8 | 2012-13 | – | 1 | 1 | 2 | – | 4 |
| 9 | 2011-12 | 1 | 1 | – | 1 | – | 3 |
| 10 | 2011-12 | 1 | 1 | – | 1 | – | 3 |
| 11 | 2010-11 | 1 | 1 | – | – | – | 2 |
| 12 | 2009-10 | 1 | – | – | – | – | 1 |
| 13 | 2008-09 | 1 | – | – | – | – | 1 |
| 14 | 2008-09 | 1 | – | – | – | – | 1 |
| Total | 7 | 5 | 6 | 4 | 2 | 24 | |